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يضيف:1002، هوانماو بناء رقم 105 ، مينغتشنغ الطريق ، خفى المدينة 230061، الصين

APIs and Intermediates
(S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diamine CAS NO:314771-76-1

(S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diamine CAS NO:314771-76-1

CAS NO: 314771-76-1
Molecular Formula: C18H16ClFN4O2
Molecular Weight: 374.797
EINECS NO:1312995-182-4
MDL NO: N/A

تفاصيل المنتج

Product Description

Product Name: (S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diamine CAS NO:314771-76-1

 

 

Synonyms:

N4-(3-Chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]-4,6-quinazolinediamine;

(S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diamine;

4-N-(3-chloro-4-fluorophenyl)-7-[(3S)-oxolan-3-yl]oxyquinazoline-4,6-diamine;

4,6-Quinazolinediamine, N-(3-chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]-

N-(3-Chloro-4-fluorophenyl)-7-[(3S)-tetrahydro-3-furanyloxy]-4,6-quinazolinediamine

 

 

Chemical & Physical Properties

Appearance :off-white solid.

Assay : ≥99.0%, EE ≥99.5%

Density: 1.5 g/cm3

Boiling Point:559℃ at 760 mmHg

Flash Point:291.9℃

 

 

Afatinib-des(4-dimethylamino-2-en-1-oxo)butyl is a reactant in the synthesis of Afatinib, an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.

 

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Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.

 


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